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Contract Services Team

Bioprocess Services

Jennifer Pancorbo, Ph.D., Director, Industry Programs and Research, leads the Bioprocess Services (BPS) group at BTEC, where she provides support for external parties looking to solve problems in process development, technology development, scale-up data generation, and material production for research and pre-clinical studies.

Dr. Pancorbo is responsible for academic courses in microbial fermentation and industry special topics; she also supports professional development courses in both upstream and downstream processing. In addition, she functioned as project coordinator for BTEC's international influenza vaccine manufacturing program.

She has over 13 years of experience in the biomanufacturing field, particularly in developing downstream purification processes and optimizing upstream production strategies for vector vaccines. Dr. Pancorbo earned a Bachelor of Science in chemical engineering and holds a doctorate in chemical and biochemical engineering, where she focused on the design and development of targeted drug delivery.

Haiwei Zhang works as a Scientist II in the Bioprocess Services group at BTEC, where he leads and participates in projects serving the needs of clients in the biotechnology industry through process development, material production, and data generation. He served as the manager of BTEC’s small-scale laboratories before joining the BPS group.

Mr. Zhang has a diverse background in biotechnology through years of working in both academia and industry. His skill set ranges from molecular cloning, imaging, and cell culture to fermentation and protein purification. He earned a Bachelor in Science in biochemistry from Nanjing University, China, and a Master of Science in natural sciences from the State University of New York at Buffalo.

Melody Lao, a Scientist II in the Bioprocess Services group at BTEC, supports the management and execution of a wide variety of projects for external clients. These projects include process development, technology development, and material production for research or pre-clinical studies.

Ms. Lao has 10 years of experience in the biomanufacturing field with expertise in cell culture process development. She joined BTEC in 2011 as a Bioprocess Training Associate for the Operations group, where she supported upstream lab courses. Prior to joining BTEC, she worked at Merck in Durham, N.C., and Cook Pharmica, a contract manufacturing organization, in the upstream process development group. She received her Bachelor of Science degree in biochemistry with a minor in chemistry from Indiana University, Bloomington.

Matt Teten joined the Bioprocess Services team as a Scientist II in January 2018 as the subject matter expert in downstream processes. He has over seven years of experience in both large- and small-scale downstream operations with a focus in process development. Mr. Teten earned his Bachelor of Science degree in biological engineering with a concentration in bioprocessing along with minors in physics and philosophy from North Carolina State University. Prior to joining BTEC, he worked as an industrial process specialist at Medicago for over two years, and later as a downstream process development scientist at Fujifilm Diosynth for five years, where he developed purification processes for several vaccines and protein therapeutics from a variety of expression systems.

Greg Worsley is a Scientist I with the BTEC Bioprocess Services group. He holds bachelor’s degrees in chemical engineering (B.S.) and chemistry (B.A.) from North Carolina State University. Mr. Worsley has over 10 years of experience in upstream processing, which he gained during his work at Fujifilm Diosynth and Biogen. His experience includes fermentation, cell culture, stainless steel, and single-use technologies. Mr. Worsley’s work has also included activities in process development, and small-, intermediate-, and large-scale manufacturing.

 

Analytical Services

Caroline Smith-Moore, Ph.D. serves as interim assistant director, Analytical. In this role, she leads a group developing assays, performing testing, and conducting research for BTEC, clients (NC State and industry), and grant-funded projects. She is heavily involved in BTEC’s gene therapy initiatives, specifically the development of assays for characterizing AAV. Additionally, she directs work in cell line development, where she was a senior scientist previously. She provides course instruction for analytical and cell line development in undergraduate, graduate, and professional development courses.

She has extensive experience in biochemical characterization, assay development, and molecular biology. She also has expertise in recombinant expression technology in prokaryotic and eukaryotic systems, as well as cell culture.

Dr. Smith-Moore earned a Bachelor of Science in microbiology, a Professional Science Master’s degree in microbial biotechnology, a Master of Business Administration degree, and a doctorate in functional genomics, all from NC State.

Mara Massel is a Bioprocess Training Associate in the Analytical lab. During the past 17 years of her career, she has focused on microbiology, developing new methods for DNA/RNA isolation, PCR/qPCR/RT-PCR, Southern blots, Western blots, DNA/RNA quantification, and sequencing. A longtime university employee, she holds a Bachelor of Arts in chemistry and a Bachelor of Science in biochemistry, both from NC State.

Brian Mosley, a Scientist II at BTEC, currently manages the Analytical Service center and is responsible for project administration and execution. He has 20 years of experience in analytical chemistry with a focus on methods development and validation in the separation sciences (HPLC, UPLC, GC). He has a wide range of experience with development of analytical methods for both large and small molecule therapeutics at all stages of the drug development process. 

Prior to coming to BTEC, Mr. Mosley spent 14 years between two contract research organizations, Catalent Pharma and BioLink Life Sciences. Both organizations perform contract testing in conformance to current Good Manufacturing Practices (cGMP), as required by the U.S. FDA. He holds a bachelor’s degree in chemistry from East Carolina University.