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Bioprocess Equipment

BTEC’s Bioprocess Services meet clients’ needs with a wide variety of state-of-the-art equipment and flexible facilities, including the following.

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Fermentation

ABB 300-L Bioreactor

ABB 300-L Bioreactor
  • ABB
  • Agitation: max 400 rpm
  • Temp: 150° C
  • Pressure: 45 psi
  • pH: 14.00
  • pO2: 200%
  • Sparge: 450 slpm
  • O2: 150 slpm
  • N2: 90 slpm
  • CO2: 90 slpm
  • Airflow overlay: 300 slpm
  • Acid/Base/Antifoam/Level Pumps
  • Impellers: 2
    • 14.5" separation
    • 8.5" from the bottom of the tank
    • 3 blades, 13" in diameter, marine or rushton
  • Tank height: 85 3/16"
  • Tank diameter: 26"
  • Shaft: 35.5" long, 1.5" diameter

Sartorius Stedim 30-L Bioreactor

Sartorius 30-L Bioreactor
  • Delta V
  • Agitation: max 700 rpm
  • Temp: 150° C
  • Pressure: 45 psi
  • pH: 14.00
  • pO2: 200%
  • O2: 45 slpm
  • Acid/Base/Antifoam/Level Pumps

Sartorius Stedim 30-L Bioreactor

Sartorius Stedim 30-L Bioreactor
  • Sartorious DCU
  • Agitation: max 700 rpm
  • Temp: 150° C
  • Pressure: 45 psi
  • pH: 14.00
  • pO2: 200%
  • O2: 45 slpm
  • Acid/Base/Antifoam/Level Pumps
  • Tank diameter: 12"
  • Tank height: 28 5/8"
  • Impellers: 2
    • 14.5" separation
    • 8.5" from the bottom of the tank
    • 3 blades—marine, 6" in diameter, or
      rushton, 13" in diameter

Sartorius Stedim 300-L Bioreactor

Sartorius Stedim 300-L Bioreactor
  • Sartorious DCU
  • Agitation: max 400 rpm
  • Temp: 150° C
  • Pressure: 45 psi
  • pH: 14.00
  • pO2: 200%
  • Sparge: 450 slpm
  • O2: 45 slpm
  • Acid/Base/Antifoam/Level Pumps

Cell Culture

Sartorius BioStat CultiBag RM

Sartorius 10056.0409.50 RM BioStat CultiBag RM
  • Up 20 L (10 L working volume)
  • Agitation: 42 rocks/min
  • Pressure: 50 mBar
  • Temp: 40° C
  • pO2: to 250%

GE Xcellerex XDR-50 Single Use Bioreactor

GE Xcellerex XDR-50 Single Use Bioreactor
  • 5O L Volume
  • Working volume min: 22 L cell culture, 25 L microbial
  • Agitation: 100 rpm
  • Condenser temp: 0–100° C
  • CO2: 0–100%
  • DO2: 0–200%
  • MassFlow Controllers
  • pH: 14.00
  • Chiller for temp control

ThermoFisher Scientific Hyclone 50-L with Finesse Control Unit

ThermoFisher Scientific Hyclone 50 L
  • Single Use Bioreactor
  • Agitation: 214 rpm
  • Temp: 40° C
  • pO2: 100%
  • 50 L working volume
  • pH and DO measurement capabilities

ThermoFisher Scientific Hyclone 50-L with Sartorius Control Unit

ThermoFisher Scientific Hyclone 50 L
  • Single Use Bioreactor
  • Agitation: 214 rpm
  • Temp: 40° C
  • pO2: 100%
  • 50 L working volume
  • pH and DO measurement capabilities

Downstream

AlFa Laval LAPX404SGP-31 Centrifuge

Alfa Laval LAPX404SGP-31 Centrifuge
  • Max speed: 9600 rpm
  • Motor frequency: 60 Hz
  • Max Density of Feed: 1100 kg/m3
  • Max Density of sediment: 1400 kg/m3
  • Max Density of Operation Liquid: 1000 kg/m3
  • Process Temp Min/Max: 0-100 deg C

GE AKTAProcess Chromatography System

GE AKTAProcess Chromatography System
  • Unicorn 5 Software
  • 6 mm tubing path
  • Flowrate: 4–180 L/hr
  • Max Pressure: 6 Bar

GE AKTA Avant 25 Chromatography System

GE AKTA Avant 25 Chromatography System
  • Unicorn Control System version 7
  • Piston pump
  • Metering flow rate (normal): 0.001–25 ml/min
  • Flow rate: column packing 0.01–50 ml/min
  • Pressure: 0 to 20 MPa (0–200 bar)
  • Gradient Flow rate: 0.25–25 ml/min
  • Quartenary: 1–25 ml/min
  • Valves: 6 standard/6 optional
  • Standard Valve Functions: Sample inlet, injection, Column, Outlet
  • Pressure sensors: 4
  • UV sensors: up to 2

GE AKTA Avant 150 Chromatography System

GE AKTA Avant 150 Chromatography System
  • Unicorn Control System version 6/7
  • Piston pump
  • Metering flow rate (normal): 0.01–150 ml/min
  • Flow rate column packing: 0.01–300 ml/min
  • Pressure: 0 to 5 MPa (0–50 bar)
  • Gradient Flow rate
  • Binary: 1–150 ml/min
  • Quartenary: 2–40 ml/min
  • Valves: 6 standard/6 optional
  • Standard Valve Functions: Sample inlet, injection, Column, Outlet
  • Pressure sensors: 4
  • UV sensors: up to 2

TECAN Freedom EVO Delivery System

TECAN Freedom EVO Delivery System
  • Liquid Handling Arm
  • Robotic Movement Arm
  • Plate Reader
  • Tshake
  • Tvac
  • Evo 100

GEA Westfalia Whisperfuge Centrifuge

GEA Westfalia Whisperfuge Centrifuge
  • Max. speed: 12,000 rpm
  • Heavy Liquid: 1.0 kg/dm3
  • Solids: 2.0 kg/m3

Millipore BioPharm Engineered Systems TFF

Millipore BioPharm Engineered Systems TFF
  • 30 L vessel
  • 5.2 - 28 L working volume
  • Buffer exchange capababilies (UF/DF)

KrosFlo KR2i TFF

KrosFlo KR2i TFF
  • Can process 1-10 L volumes
  • Data collected electronically
  • Automated process control
  • Flow rates greater than 3 L/min