Trends and Emerging Technologies in Downstream Biopharmaceutical Processing

Downstream

This course can count toward your Professional Certificate in Biomanufacturing Science.

Why should you take this course?

The impact of biopharmaceuticals on human health has been significant. They are used to treat, cure, or prevent a wide range of diseases, including diabetes, the flu, measles, COVID-19, numerous cancers, stroke, heart attack, spinal muscular atrophy, various eye diseases…and the list goes on. Downstream processing of biopharmaceuticals involves steps to recover, purify, and formulate product and is essential to producing safe and effective medicines. Further, it is desirable that future processes improve security of supply, reduce operating and capital costs, have enhanced flexibility to accommodate increasingly diverse products, enable faster speed (of products) to market, and lessen environmental impact.

This course will consider trends in downstream processing and emerging downstream technologies that may help to realize this vision for downstream processing. The course is self-paced and delivered totally online. This on-demand format enables participants to access—for 90 days—a series of recorded lectures with interactive components that have been created for independent, self-paced learning. Optional content that provides basic information on biopharmaceutical products and conventional processes is also included for those participants who need a refresher.

Participate and you will learn

A vision for the future of biopharmaceutical manufacturing involving less expensive manufacturing, more flexible processes, and less environmental impact;
Recent trends that are helping to meet this future vision;
Emerging unit operations that may help to realize this vision;
Underlying principles, implementation status, and drivers for use of the unit operations covered. These include single-use centrifugation, single-pass tangential flow filtration, precipitation, crystallization, and aqueous two-phase extraction. The course also covers latest advances in chromatography.

Who should participate

Scientists with some experience in downstream bioprocessing who are interested in the latest technologies and methods available. These individuals may include the following:

Process development scientists and process engineers designing downstream processes
Manufacturing managers and directors involved in downstream manufacturing
Process validation scientists
Vendors of downstream processing technologies interested in where the technology may be heading
Faculty and graduate students working in the area of downstream biopharmaceutical processing

Course format

This online course is self-paced; it does not include any scheduled meetings or other real-time events. Instruction is provided through recorded lectures that may be accessed whenever convenient. After registering, you will have 90 days to access the materials on the course website, which is always available except for brief maintenance periods. It’s estimated that the course will take approximately 14 hours to complete. Note that although lecture recordings are not downloadable, PDF versions of slides are available to participants.

Modules

Materials are divided into four modules, listed below, and each module contains several lessons.

Drivers and Trends
Centrifugation and UFDF Technologies
Chromatography
Non-conventional Technologies

Instructors

Register and you will receive

Access to approximately 14 hours of online materials
Course certificate upon completing all course materials

Fee

$499

Payment

Payment by credit card must be made at the time of registration. Prior to registration, please direct any questions to mswoodya@ncsu.edu.

Pre-course communication

Upon successful registration for a course, you will receive an automatically generated email with information about how to access the online materials. If you do not receive this email within one business day of registering, please contact Serena Hodge, Industry Training Coordinator, at shodge@ncsu.edu.

Extensions

After registering, you will have 90 days to complete the course, which is always available (except for brief maintenance periods). Requests for extensions beyond the 90 days must be requested within 30 days of course access end date and will be considered on a case-by-case basis. Extensions are limited to one additional 30-day access window.

Short course cancellations

CANCELLATION BY REGISTRANT

Enrollment may be canceled within 10 business days (minimum two weeks) of the registration, subject to the conditions noted below. A 50% cancellation fee is charged for each registration canceled. Refund of the remainder of the registration price is subject to the following conditions:

The course material must not have been accessed by the registrant.
The registrant must request the cancellation within 10 business days of the registration.

To cancel a registration and be eligible for a refund of course fees, you must notify BTEC by e-mail to mswoodya@ncsu.edu.

CANCELLATION BY BTEC

Cancellation by BTEC does not apply to this course.