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From Capture to Polish: Using Mixed-Mode and High-Resolution Chromatography Resins for Virus Purification and mAb Aggregate Removal
Join Bio-Rad Laboratories at BTEC to learn about unique resin selectivities for process purification and best practices to purify challenging biomolecules. The key takeaways of this session are:
- How different mixed-mode selectivities affect virus purification
- The ease of aggregate clearance using mixed-mode resins
- Selecting the best resin to maximize impurity removal
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Agenda
| Time | Event |
|---|---|
| 09:00 – 09:30 | Registration |
| 09:30 – 09:40 | Welcome |
| 09:40 – 10:20 | Cation exchange‑calcium affinity mixed‑mode media: How it works and how to screen it. Case study—mammalian virus purification |
| 10:20 – 11:00 | Hydrophobic cation exchange media: How it works and how to screen it. Case study—adenovirus purification |
| 11:00 – 11:20 | Aggregate Clearance with mixed mode resins |
| 11:20 – 11:40 | High‑resolution cation exchange resin for product‑related impurity removal: dimers, aggregates, and charge variants |
| 11:40 – 12:00 | Optimizing your purification system for screening resins |
| 12:00 – 13:00 | Lunch and open discussion |
Following the last presentation, lunch will be served and attendees will have the opportunity to discuss the complexities of process development and how to streamline the purification process.