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Next-Gen Biologics Manufacturing: How Far, How Close?

Thursday, Mar. 28, 2024
9:00 – 10:00 a.m. ET
BTEC room 123
Zoom: go.ncsu.edu/next-gen-biologics

While a large portion of R&D development is directed towards discovering new biomolecules and biological products, less attention is paid to manufacturing and scalability of these discoveries. In this talk, several examples for scale-up challenges of biological products will be demonstrated. Next, concepts and tools integrations from a process systems perspective to develop next-generation of biologics manufacturing are discussed to further extend and develop affordable and accessible food, materials, drugs and energy through industrial biotechnology.

Speaker

Seyed Soheil Mansouri, Ph.D.
Associate Professor, Department of Chemical and Biochemical Engineering
DTU

Dr. Seyed Soheil Mansouri is an Associate Professor in the Department of Chemical and Biochemical Engineering at the Technical University of Denmark (DTU) and affiliate faculty at Sino-Danish Center for Education and Research in Beijing, China. He received his PhD (2016) and MSc (2013) in chemical and biochemical engineering both from DTU. His current research is focused on Process Systems Engineering, System Dynamics, Computational Agility (AI and Quantum Computing), Socio-Economic-Technological Analysis of Complex Dynamic Systems, Process Synthesis, Design, Control and Intensification with focus on Chemical, Pharmaceutical and Bio-manufacturing sectors. He is a senior member of American Institute of Chemical Engineers (AIChE) and Danish representative to Computer Aided Process Engineering (CAPE) Working Party of European Federation of Chemical Engineers (EFCE). He serves as treasurer and board member of European Committee for the Use of Computers in Chemical Engineering Education (EURECHA). His is also international exchange coordinator for AIM-Bio project, 27 million USD project between DTU and NC State University funded by Novo Nordisk Foundation. Furthermore, he is involved in Biosolutions Zealand as a major partner to develop a biomanufacturing powerhouse in Zealand Region of Denmark with a total funding of close to 12 million USD funded by European Regional Development Fund. Dr Mansouri develops methods and tools within the domain of Process Systems Engineering (PSE). This is an interdisciplinary field within Chemical and Biochemical Engineering that its main objective is development of systematic procedures based on mathematical models and computational techniques for the analysis, design, operation, control and optimization of process systems. Recently, he has engaged in the Biosolutions Zealand project to design, develop and tackle the economics of scale associated with production systems for biomolecule scale-up combining PSE and pilot-scale validation. He is also engaged in range of strategic partnerships with international companies such as 21st.BIO (Denmark), Henkel AG (Germany), and Zapata Computing (USA).

Presented by AIM-Bio.